The Holokaustos, as in great destruction by fire, is a Greek word that refers to the future event of global destruction that is primarily described in the Book of Revelation. The Greek word is the basis for the English word holocaust.
Mystery Babylon is a nation that will be destroyed by fire and other judgments. While her identity remains a subject of debate, a growing number of prophecy students who believe that Mystery Babylon is the United States of America. The main destruction of Mystery Babylon will occur within a single hour (Rev 18:10), a very curious detail that becomes more compelling when considering the current state of technology. There are a number of ways in which that could play out and all configure together, including: electromagnetic pulse, cyber attack on the national grid, natural disasters, and conventional warfare.
Revelation 8:6-11 describes Trumpets #1 through #3 (hail and fire mixed with blood; a great mountain burning with fire; and the deep impact event of Wormwood).
6 And the seven angels which had the seven trumpets prepared themselves to sound.
7 The first angel sounded, and there followed hail and fire mingled with blood, and they were cast upon the earth: and the third part of trees was burnt up, and all green grass was burnt up.
8 And the second angel sounded, and as it were a great mountain burning with fire was cast into the sea: and the third part of the sea became blood;
9 And the third part of the creatures which were in the sea, and had life, died; and the third part of the ships were destroyed.
10 And the third angel sounded, and there fell a great star from heaven, burning as it were a lamp, and it fell upon the third part of the rivers, and upon the fountains of waters;
11 And the name of the star is called Wormwood: and the third part of the waters became wormwood; and many men died of the waters, because they were made bitter.
Revelation 9:15-18 has been identified by some students as World War IV (yes, 4. WW3 may happen during the Seals, or before then)
15 And the four angels were loosed, which were prepared for an hour, and a day, and a month, and a year, for to slay the third part of men.
16 And the number of the army of the horsemen were two hundred thousand thousand: and I heard the number of them.
17 And thus I saw the horses in the vision, and them that sat on them, having breastplates of fire, and of jacinth, and brimstone: and the heads of the horses were as the heads of lions; and out of their mouths issued fire and smoke and brimstone.
18 By these three was the third part of men killed, by the fire, and by the smoke, and by the brimstone, which issued out of their mouths.
Revelation 16:8-9 (a solar scorching)
8 And the fourth angel poured out his vial upon the sun; and power was given unto him to scorch men with fire.
9 And men were scorched with great heat, and blasphemed the name of God, which hath power over these plagues: and they repented not to give him glory.
Revelation 18:7-10 (Mystery Babylon destroyed by fire in one hour)
7 How much she hath glorified herself, and lived deliciously, so much torment and sorrow give her: for she saith in her heart, I sit a queen, and am no widow, and shall see no sorrow.
8 Therefore shall her plagues come in one day, death, and mourning, and famine; and she shall be utterly burned with fire: for strong is the Lord God who judgeth her.
9 And the kings of the earth, who have committed fornication and lived deliciously with her, shall bewail her, and lament for her, when they shall see the smoke of her burning,
10 Standing afar off for the fear of her torment, saying, Alas, alas that great city Babylon, that mighty city! for in one hour is thy judgment come.
“I know not with what weapons World War III will be fought, but World War IV will be fought with sticks and stones.” --Albert Einstein .